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按这个岗位的城市和方向提醒，确认后才开启，可选择每日或每周。
上海蛋白科学家岗位，负责治疗性蛋白的设计表达纯化表征、SPR及生物物理分析、蛋白结晶与X射线衍射数据收集与初步结构分析，高级岗位需具备项目领导力。
About The Role
We are seeking a motivated scientist in the area of Protein Science and Biostructure, including biochemical and biophysical methods. A successful candidate should play key roles in target validation and protein design and production, hit identification, hit validation by biophysical method. She or he responsibilities also will include X-ray Crystallography.
Responsibilities
Design, express/purify, and characterize proteins of therapeutic interest.
Perform SPR and biophysical assay to characterize protein-ligand, protein-protein, interactions
Perform protein crystallization and X-ray, collect diffraction data.
Preliminary structural analysis.
For senior scientist, Associate Director
Excellent presentation, writing and coaching skills.
Experience preferred in program leadership: high level skills leading a drug discovery program to success, leveraging know-how & accountability from areas outside your own area of expertise and function.
Experience working in new directions, building new platforms or bringing in new methods/technologies in protein science
MS or PhD (or relevant experience) in protein chemistry, biochemistry, enzymology or biophysics with 3-5 years of drug discovery experience. Experience in pharmaceutical or biotech company is preferred.
Excellent publication and established track record.
Solid knowledge and experience in expression vector construction, multiple protein expression systems and various purification techniques.
Expertise in biophysical techniques including SEC-MALS, SPR, ITC and TSA, etc.
A good record in developing enzymatic assays including enzyme kinetic and thermodynamic mechanisms or deep understanding on protein LCMS techniques is plus.
研究和试验发展
