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负责开发计算结构生物学策略以支持mRNA发现与开发;运用AlphaFold等工具预测蛋白质及RNA结构,结合机器学习与分子建模解决复杂问题;与平台及治疗研究团队紧密合作,要求PhD背景及Python/R编程能力。
Responsibilities:
· Develop and implement computational structural biology strategy to support mRNA discovery and development.
· Lead to use and develop computational tools to understand biological molecule structures, such as protein and RNA, as well as their interactions.
· Develop and implement state-of-the-art computational tools and methods to solve complex problems in mRNA discovery and development.
· Design molecular structure-based experiments and work closely with biologists to generate and analyze the data.
· Build and maintain strong collaborations with Platform and Therapeutical research team.
Requirements:
· PhD in computational structural biology, chemistry, bioinformatics, or related field with a minimum of 1+ years of experience in computational structural biology.
· Strong hands-on expertise in predicting protein structure, such as using AlphaFold.
· Demonstrated experience in machine learning and molecular modeling.
· Strong programming skills in Python, R, and other programming languages.
· Experience with cloud computing and high-performance computing environments.
· Excellent communication and interpersonal skills, including the ability to effectively collaborate with both internal stakeholders.
· Experience in drug discovery and development, including experience in a biotech or pharmaceutical company, is
highly preferred.
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